Dr. Bradeen research focuses on the functional and evolutionary genomics of disease resistance in plants. He is especially interested in the use of crop wild relatives to improve disease resistance in the agricultural production setting. Working within the potato-Phytophthora infestans (late blight) pathosystem, his lab studies how plants regulate disease resistance responses as a function of plant age and organ type and translate that knowledge into production practice. Working in the Rosaceae and the Solanaceae, they are also developing novel data visualization informatics enabling comparative genomics of disease resistance gene components across the genomes of related plant species. This line of research leads to new insights into plant genome evolution, the molecular basis of non-host resistance, and marker aided selection for plant improvement.